Whether vasculitis is serious or not cannot be generalized and needs to be judged according to the actual condition of the patient, but most vasculitis is serious. 1. Vasculitis is a group of diseases characterized by inflammation and necrosis of blood vessel walls or perivascular tissues. The cause of vasculitis is mostly unknown, and the severity varies with the type, size, location, and pathologic characteristics of the affected vessels. 2. Vasculitis can produce clinical manifestations of insufficient blood supply to the corresponding tissues and organs. If the patient’s vasculitis occurs in the renal artery, coronary artery and other parts of the body, it may lead to kidney damage, myocarditis and other visceral symptoms, and with the development of the disease, it will also have a serious impact on the patient’s health, which will be more serious at this time. 3. Infections, tumors, drugs, chronic inflammatory diseases and other factors can also destroy blood vessels, or lead to immune complexes deposited in the blood vessel wall, or cell-mediated immune abnormalities, causing vascular inflammatory response, secondary vasculitis. When severe vasculitis is combined with severe infections and neoplastic diseases, the condition is often severe. It is recommended that patients with suspected vasculitis seek medical attention in a timely manner and actively cooperate with their doctors to avoid delaying their condition.