Persistent intracranial murmur, a persistent murmur like the roar of a machine, aggravated by heart contraction, often interfering with sleep, can be heard in the frontal area with a stethoscope, and the murmur diminishes or disappears when the affected common carotid artery is compressed with a finger. Fractures at the base of the skull can cause injury to the cavernous sinus segment of the internal carotid artery or its branches, or direct injury to the artery from firearm injury or sharp force injury, or rupture of the wall of the internal carotid artery in the sinus segment from the violent turbulent blood flow during trauma. These factors can also cause punctate hemorrhage or limited injury to the arterial wall, and later rupture of the cavernous sinus segment due to violent fluctuations in blood pressure. So, how should patients with sustained intracranial murmur caused by intracranial fracture be prevented and treated? The following is a brief introduction: 1, should pay attention to the rational structure of the diet, and to develop good eating habits. 2, to maintain a good spirit and emotion, and strive to “treat people with generosity and optimism”. 3.Simple skull base fracture does not need special treatment, mainly observe whether there is brain injury and deal with cerebrospinal fluid leakage, cranial nerve injury and other comorbidities. When combined with cerebrospinal fluid leakage, intracranial infection must be prevented, occlusion or flushing is contraindicated, and lumbar puncture is contraindicated. Rest in a head-high position and avoid coughing, sneezing and blowing the nose as much as possible. Administer antibiotics intravenously or intramuscularly. Most leaks heal on their own within 1-2 weeks after the injury. Surgery may be considered for those who have not stopped leaking for more than a month.