The 4-valent vaccine to prevent cervical cancer is for women between the ages of 9 and 45. Each stage of the cervical cancer prevention vaccine has a different age limit for prevention. The age group for the bivalent vaccine is 9~45 years old. The age group for the nine-valent vaccine is 16 to 26 years old. Quadrivalent HPV vaccine was first applied to women aged 20 to 45 years old, and in November 2020, the State Drug Administration approved the quadrivalent HPV vaccine to be applied to women aged 9 to 19 years old, so the cervical cancer 4-valent vaccine, which is suitable for women between the ages of 9 and 45 years old. Timely injection of cervical cancer 4-valent vaccine, not only for low-risk HPV6 and HPV11 can play a preventive role, but also for HPV16 and HPV18 have a certain preventive effect. The 4-valent cervical cancer vaccine should be injected three times, the second injection should be given two months after the first one, and the interval between the third and the first one should be six months, so as to play a good preventive role. Cervical cancer 4-valent vaccine should not be injected during pregnancy, and contraception should be used during the vaccination period.