Severe tuberculosis
Definition: Broad: refers to TB patients who have one or more organ failure at the same time.
Narrow sense: TB causing failure of one or more organs
Six failures: heart failure, brain failure, respiratory failure, liver and kidney failure, shock
Classification.
1, tuberculosis leading to organ failure
For example, tuberculosis leads to respiratory failure or pulmonary heart failure, nodal brain failure, etc.
2. Tuberculosis itself does not lead to organ failure but is combined with other diseases that lead to organ failure.
For example, tuberculosis and heart disease leading to heart failure, etc.
3.Tuberculosis leads to organ failure and combined with other diseases of organ failure.
For example, tuberculosis combined with kidney failure, etc.
4.Serious adverse drug reactions in the course of anti-tuberculosis treatment lead to organ failure
For example: anti-tuberculosis drugs cause liver failure, etc.
5.Potential (risky) severe tuberculosis: on the one hand tuberculosis; on the other hand; other diseases
Tuberculosis leading to organ failure
I. Tuberculosis
Common tuberculosis leads to respiratory failure, pulmonary encephalopathy, etc. and even multi-organ failure.
1. Hematogenous tuberculosis: diffuse lung lesions leading to acute damage to lung tissue and fever
2, secondary chronic fibro-cavernous tuberculosis
3. Caseous pneumonia:
Large solid lesions in the lungs affecting lung function leading to respiratory failure, or severe infection or tuberculosis bacteraemia
4, Bronchial tuberculosis:
Large airway narrowing or obstruction: diffuse small airway obstruction or spasm
5, primary tuberculosis with multiple hilar or mediastinal lymph node enlargement
6, multidrug-resistant or super multidrug-resistant or multi-drug-resistant tuberculosis
7, atypical Mycobacterium tuberculosis
8, special: non-tuberculous mycobacteria
Common hemorrhagic shock due to pulmonary tuberculosis
1, tuberculosis hemoptysis: pulmonary tuberculosis lesions or cavities invade blood vessels
2, TB branch enlargement hemoptysis.
3, tuberculosis vascular malformation or hemangioma rupture
Tuberculosis or and serious infection
1. Tuberculosis infection
2.Tuberculosis and serious infection (drug-resistant bacteria infection or fungal infection)
3.Tuberculosis and severe mixed infection (multiple infections)
Complications or sequelae of tuberculosis
Chronic obstructive pulmonary disease (COPD), respiratory failure, pulmonary heart disease, etc.
Common extrapulmonary tuberculosis
Tuberculosis of the brain causing organ failure
Tuberculous meningitis or meningoencephalitis
1. Hydrocephalus
2.Brain herniation
3, lesions compressing nerve reflexes, blood vessels, etc.
4.Obstruction or stenosis of the spinal canal, etc.
5.Intracranial infection.
Pleural effusion Pericardial effusion Peritoneal effusion or multiple simultaneous multiple plasma cavity effusion
1, abscess chest or abscess pneumothorax hemopneumothorax tracheobronchial pleural fistula and severe infection.
2, pericardial tamponade or constrictive pericarditis leading to heart failure, etc.
3.Severe abdominal infection Abdominal adhesion lacerations leading to hemorrhage, etc.
Lymphatic tuberculosis
1.Massive cervical or supraclavicular lymph nodes compressing large blood vessels or nerves.
2.Mediastinal lymphatic tuberculosis compressing blood vessels or nerves or rupture leading to severe infection of the thoracic cavity
3, rupture of abdominal or retroperitoneal lymph nodes leading to severe infection, etc.
Gastrointestinal tuberculosis or intestinal tuberculosis
1.Intestinal tuberculosis leading to complete or incomplete intestinal root block or perforation or hemorrhage or serious infection in the abdominal cavity
2. Gastrointestinal tuberculosis leading to gastrointestinal hemorrhage, etc.
Bone tuberculosis
1. vertebral fracture due to tuberculosis of the spine (cervical, thoracic, lumbar, caudal) 1) compression of blood vessels or nerves 2) bleeding due to injury to large blood vessels
2. Abscess formation 1) compression of blood vessels and nerves 2) severe infection, etc.
Urological tuberculosis or renal tuberculosis
1. Renal tuberculosis leading to renal failure or bleeding due to damage to blood vessels
2. Ureteral stenosis or blockage due to urological tuberculosis
Adrenal tuberculosis
1.Adrenal crisis
2.Electrolyte disorders
3, endocrine disorders, etc.
Liver tuberculosis
1.Hepatic necrosis or liver failure
2.Hepatic hemorrhage
Others
Serious adverse drug reactions during anti-tuberculosis treatment leading to organ failure
The following are common
1. Liver failure due to drug-related liver damage
2.Renal failure due to drug-related renal damage
3. Hematologic damage: reoccurrence, hematogenous anemia, granulocyte deficiency, leukemia, etc.
4.Other