A low-grade fever is not necessarily a coronavirus infection. There are many symptoms of coronavirus infection, and low-grade fever is one of them. It is not the only symptom that can determine coronavirus infection. Coronavirus infection is an acute respiratory infectious disease, the main symptoms of patients are fever, dry cough, general weakness, some patients also have a sore throat, nasal congestion, diarrhea, loss of taste and smell, muscle pain. Diagnosis of coronavirus infection requires pathogenetic testing, such as multiplex PCR nucleic acid testing, and further serologic and imaging tests. There are many reasons for low fever, such as bacterial and viral infections, secretion and metabolic diseases, oncological diseases, etc. It is not necessarily coronavirus infection, and it is recommended that the patient consult a doctor in time for a professional examination to find out the cause of the disease and carry out targeted treatment.