After taking progesterone, withdrawal bleeding usually occurs 3-5 days after stopping the medication, no later than 7 days. If the menstrual flow does not come after 7 days of progesterone discontinuation, it is more likely to be caused by improper progesterone usage, pregnancy, insufficient estrogen levels, cervical adhesions, cervical canal adhesions, etc. You need to go to the hospital and be treated by a professional doctor to clarify the causes. Common causes and treatment 1. Inappropriate usage: Patients who fail to take progesterone as prescribed by their doctors, omit to use it during the medication period or do not take enough total amount of medication can affect the subsequent menstruation. It is recommended to take progesterone strictly under the guidance of a doctor, and if there is any omission, you should consult your doctor in time to remedy the situation. 2. Pregnancy: If you are a woman of childbearing age, have a normal sexual life history, and have not had your period for 7 days after stopping progesterone, you should highly suspect the possibility of pregnancy. You can go to the hospital to perform blood HCG test or buy pregnancy test paper to detect; 3. Insufficient estrogen level: it can lead to poor endometrial hyperplasia, and even if you stop taking progesterone for 7 days, your menstruation cannot come. It is necessary to improve the diagnosis of the 6 sex hormone tests and follow the doctor’s instructions to supplement estrogen and then take progesterone. 4. Cervical adhesions and cervical canal adhesions: If there are cervical adhesions and cervical canal adhesions, the uterine wall cannot be thickened as planned after performing uterine surgery, such as abortion and curettage, so there is no menstrual flow and the effect cannot be achieved. Further ultrasound and hysteroscopy need to be improved to clarify the diagnosis of uterine adhesions and cervical canal adhesions. Hysteroscopic surgical treatment is needed, and if necessary, open surgery can be performed. Progesterone is a progestational drug. Consult your physician before use and enforce it strictly. It is not recommended for patients without progesterone indications.