Raynaud’s phenomenon is usually not serious, the patient after timely and effective treatment, the general prognosis is good, most will not cause serious consequences; but there are individual patients with serious condition, the attack is persistent, when serious, can appear fingertip ulcers gangrene and so on. Raynaud’s phenomenon refers to the vascular nerve dysfunction, triggered by the small arterial spasm of the extremities of the disease, the patient may have the distal end of the fingers (toes), tongue and other places of cyanosis, redness, accompanied by local numbness, pain, burning sensation and other uncomfortable symptoms, cold or emotional tension stimulation can aggravate the above discomfort. Generally, after drug treatment such as Tolazoline Hydrochloride, Methyldopa and other medications, as well as limb negative pressure, surgery and other timely and effective treatment, a better prognosis can be obtained, and the condition can generally be significantly controlled. However, if not timely and effective treatment, individual patients with severe disease episodes can be persistent, intermittent almost disappeared, there are local tissue trophic changes, such as skin atrophy or thickening, nails are longitudinally curved deformity, finger pads emaciation, decalcification of the terminal phalanges, fingertip ulcers gangrenous, and may face amputation of the finger (toes), the serious can affect the lives of the patients. It is recommended that patients with Raynaud’s phenomenon should consult a doctor in time, and follow the doctor’s instructions to standardize the treatment, so as not to continue the progress of the disease and jeopardize the health of the body.