Heart fibrillation in liver cancer patients is usually related to malnutrition, hepatic encephalopathy, hepatic ascites and other factors. 1. Malnutrition: when liver cancer patients’ body develops malignant fluid state, it may cause reflexive heart fibrillation, which leads to rapid heartbeat. 2. Hepatic encephalopathy: it belongs to the complications of liver cancer patients. Further progression of the disease causes hepatic coma, which leads to cerebral edema easily after the increase of blood ammonia, thus resulting in increased heart rate and respiration. 3. Hepatic ascites: further aggravation of liver cancer will cause hepatic ascites, which will lead to hydroelectrolyte disorders in the decompensated stage, resulting in portal hypertension, which will easily cause increase of right atrial blood volume, thus causing cardiac fibrillation. There may be other reasons for heart fibrillation in liver cancer patients, it is recommended to consult doctor in time and standardize the treatment under the guidance of professional doctors, and inhale oxygen when necessary to ensure the airway is open to avoid asphyxiation and other adverse consequences.