Urine protein + is the presence of protein inside the urine more than 100mg/L or 150mg/24h. In general, healthy people perform routine urinalysis, suggesting that urinary protein -, if the total amount of protein in the urine is greater than 150mg/24h or random urinary protein concentration is greater than 100mg/L, then it can cause urinary protein +. There are many factors that cause an increase in proteinuria, which can generally be divided into physiologic proteinuria and pathologic proteinuria, of which, pathologic proteinuria is more serious and needs to be treated aggressively for the cause. Physiological proteinuria is common in cases of strenuous exercise, fever, cold, nervousness, etc. Generally, proteinuria is less, and after rest, most of them can return to normal, without special treatment. Pathological proteinuria is mostly caused by renal diseases, such as primary glomerular disease, secondary glomerular disease, tubulointerstitial disease, hereditary nephropathy, urinary tract infections, urinary stones, etc., which can be standardized according to different causes and medical advice. When the patient urinary protein +, should be timely regular hospital medical treatment, standardized treatment in accordance with medical advice, in order to avoid further development of the disease condition.