Urticaria is not immune deficiency. Urticaria is a common skin disorder in which there is a temporary increase in vascular permeability in the skin mucosa causing limited edema. The exact cause cannot be found in most patients. Common causes include food (animal proteins, plants, food additives, etc.), infections (hepatitis viruses, coxsackie viruses, streptococci, fungi, parasites, etc.), drugs (penicillin antibiotics, serum preparations, various vaccines, etc.), respiratory inhalants, and skin contacts (pollen, animal dander and hair, dust mites, etc.). Physical factors (cold, heat, sunlight, friction and pressure), mental and endocrine factors and genetic factors can also cause urticaria. In addition, some systemic diseases (systemic lupus erythematosus, malignant tumors, metabolic disorders, endocrine disorders, autoimmune thyroiditis, ulcerative colitis, etc.) can also be associated with this disease. Therefore, the occurrence of urticaria does not mean that the immune system is reduced, when the recurrence of urticaria, we should consult a doctor in a timely manner, under the guidance of the doctor to clarify the cause of urticaria after reasonable treatment.