The root of the second toe of the left foot hurts when pressed according to the cause of the treatment, common causes are trauma, gout and rheumatoid arthritis, etc., the treatment methods are cold compress, hot compress, drugs and functional exercises. 1. Trauma: trauma to the left foot, the second toe root muscle and other soft tissue injuries, pain when pressed, acute injuries require rest, cold compresses within 72 hours to reduce swelling and pain, more than 72 hours of hot compresses to promote blood circulation can reduce pain symptoms. 2. Gout: it can cause the second toe joint of the left foot to deposit uric acid crystal salt, there will be pain when pressed, if the pain is mild, avoid eating food containing high purine, such as seafood, animal offal, etc., generally no special treatment, if the pain is more serious, you can take analgesic and anti-inflammatory drugs, such as celecoxib. At the same time also need to take oral anti-gout drugs such as colchicine and allopurinol. 3. Rheumatoid arthritis: rheumatoid arthritis can be the second toe joint cartilage and bone tissue of the left foot, it will hurt when pressed, if there is smoking should first quit smoking, can take methotrexate, leflunomide, etc. for anti-rheumatic treatment. The root of the second toe of the left foot hurts when pressed, and there may be other reasons, if no improvement or aggravation through rest, you should go to the regular hospital in time to see a doctor to determine the cause of the disease according to the specific condition, and give the correct treatment for the cause. The above drugs should be used under the guidance of a doctor.