An acromegaly is a patient suffering from acromegaly, which is also known as amyotrophic lateral sclerosis. The cause of the disease is mainly related to genetic factors, and may also be caused by long-term exposure to toxic substances, nutritional factors, infectious factors and other reasons. 1. Genetic factors: the disease has a family history of inheritance, usually autosomal dominant inheritance, such as parents, siblings, siblings, their relatives with the disease, the probability of their relatives significantly increased, the probability of its incidence is much higher than that of the rest of the normal population. 2. Long-term exposure to toxic substances: for example, long-term exposure to metal aluminum, organic solvents, pesticides and other toxic substances, often increase the incidence of amyotrophic lateral sclerosis. 3. Nutritional factors: some studies have found that when the human body lacks vitamin B1 and other nutrients, resulting in nutritional disorders, may increase the incidence of amyotrophic lateral sclerosis. 4. Infectious factors: the development of amyotrophic lateral sclerosis is often associated with human immunodeficiency virus, prions and other pathogens. Through the immune function test, it can be found that the patients’ cerebrospinal fluid immunoglobulin is obviously elevated, and the function and number of T cells in the blood are abnormal. Amyotrophic lateral sclerosis has many causes and should be detected and treated as early as possible.