Due to the increasing standard of living and changes in dietary habits, there are more and more patients with gallbladder stones in China, and many people are found to have gallbladder stones when they attend routine medical checkups or feel abdominal discomfort. In the summer before last, a young girl with a sad face came to me at the Department of Lumpectomy of the First Hospital of Wenzhou Medical College. The girl said that in the past two years, she often had vague pain in the upper abdomen after eating fatty food, and had always thought it was a stomach problem. This time, the ultrasound found gallbladder stones during the physical examination for the civil service exam in her hometown, and the local doctor recommended her to have a cholecystectomy. She was worried that having her gallbladder removed at a young age would have side effects on her body, and she was also afraid that it would affect her hard-earned job. I reviewed her abdominal ultrasound and found that she only had 2 stones in her gallbladder, one 15 mm in length and the other 11 mm in diameter, and the gallbladder wall was not thick and the gallbladder contraction was normal. After the anesthesia, three small 0.5-1.0 cm holes were made in her belly (one of them was cleverly concealed at the navel), and a high-definition laparoscope was used to observe the abdominal organs comprehensively, then a small incision was made at the bottom of the gallbladder, and the two stones were successfully removed. The small incision on the gallbladder was closed with absorbable sutures. She was discharged from the hospital the day after the operation. For more than 2 years, her abdominal pain has been gone and she came to the clinic last Tuesday for a follow-up ultrasound and her gallbladder was normal. The human gallbladder has an important physiological function. The bile secreted by the liver is first stored in the gallbladder, and the gallbladder mucosa has a strong function of absorbing water and electrolytes, and the bile can be concentrated 5-10 times, and when eating, the gallbladder contracts and discharges the bile into the duodenum to help digestion and absorption of fat. After cholecystectomy, some patients will present with postoperative bloating and diarrhea and dyspepsia due to the direct and continuous drainage of bile into the small intestine. What’s more, about a quarter of patients with gallbladder stones are asymptomatic for life and do not require any treatment. Therefore, patients with newly discovered or perennially asymptomatic gallbladder stones generally do not require aggressive surgical treatment, as long as they adopt a good lifestyle, eat less fatty foods, do not drink or smoke heavily, and have their abdominal ultrasound reviewed regularly. When you find gallbladder stones and have mild gastrointestinal symptoms or fear complications from gallbladder stones, ultrasound suggests a small number of gallbladder stones, smooth gallbladder wall and good gallbladder function, and you do not want to lose your gallbladder prematurely, then you can choose minimally invasive cholecystectomy. If you have the following conditions: recurrent biliary colic, gallbladder filled with stones, gallbladder atrophy, significant thickening of the gallbladder wall, multiple small gallbladder stones with secondary common bile duct stones or pancreatitis, gallbladder neck duct stone impaction, gallbladder fluid and pus accumulation, gallbladder stones larger than 3 cm, etc., then you need to remove the gallbladder and laparoscopic cholecystectomy is preferred.