In Chinese medicine, “fire” refers to internal heat, and there is no clear contraindication between Wu Zi Diffractive Zong Pills and Jin Lock Fu Jing Pills. Under normal circumstances, they can be used together in the treatment of spermatorrhea and premature ejaculation caused by renal deficiency, and generally do not cause the manifestation of “fire”. 1. Wu Zi Diffractive Zong Pill has the effect of tonifying the kidney and benefiting the essence (replenishing the kidney essence in the body). It can be used for the treatment of impotence and infertility, spermatorrhea and premature ejaculation, lumbago, and residual leaking after urination caused by kidney deficiency and essence loss. When using this medicine, it should be noted that patients with cold and fever should not take it. At the same time, it is advisable to abstain from sexual intercourse during treatment. 2. Jinliao Guoxin Pill has the effect of fixing the kidney and astringent essence. It can be used for the treatment of kidney deficiency, spermatorrhea and ejaculation, fatigue (mental exhaustion, physical weakness), limb weakness, lumbago, tinnitus and other diseases. The adverse effects of the drug are not clear, but avoid eating spicy and stimulating food during the period of taking the drug. In conclusion, Wu Zi Diffractive Zong Wan and Jin Lock Gu Jing Wan can be used together in the treatment of spermatorrhea and premature ejaculation caused by kidney deficiency, and generally will not cause “on fire” manifestation. If necessary, it is recommended to go to a regular hospital for treatment under the guidance of a professional physician.