Parkinson’s disease is a chronic disease that occurs in middle-aged and elderly people. Once it occurs, it usually does not remit automatically, and the disease mostly develops slowly and requires long-term treatment. It is an uncontrollable abnormal movement that occurs in Parkinson’s disease after long-term treatment with dopa preparations. The term “dyskinesia” was previously translated as “movement disorder”, and its English counterpart is now mostly referred to as xerokinesia because the concept of “dyskinesia” is too general and the corresponding “movement disorder” is easily confused. The patient goes from inability to move to the other extreme: uncontrollable movement, which causes great pain to the patient. ”Heterokinesia is often characterized by involuntary or choreiform hyperactivity or dystonia of the trunk and limbs. There are three types: 1. Peak dose of agnosia or dystonia is the most common form of agnosia. Treatment: Switch to a sustained-release dosage form or reduce the dose of levodopa and increase the dopamine agonist, add a COMT inhibitor, and discontinue the MAO-B inhibitor. Isokinetic disorder in the peak phase of the formulation can be controlled with a small amount of antipsychotic medication (e.g., sulpiride or clozapine); 2. Off-phase isokinetic disorder or dystonia. It appears when the effect of each dose of levodopa wears off, and is more common with leg and foot spasms. For those who appear in the daytime, long-acting dopamine agonists (Xelianxing, Crepa) are more effective; for those who appear with painful spasms, try Chiropractic (Lioresin), which is prone to psychiatric symptoms. For local painful spasms can be local injection of botulinum toxin to relieve; 3, biphasic isokinetic disorder: the above two isokinetic disorders in the same patient, more difficult to deal with. Dopamine receptor agonists can be added. If the heterokinesis affects the patient’s daily life and fails to be resolved even after adjustment of medication, surgical treatment can be considered. Deep brain electrical stimulation is a new international treatment for Parkinson’s disease in recent years, which uses microelectrical pulse transmitters buried under the skin connected to microelectrodes to continuously stimulate certain nuclei in the deep brain to relieve the patient’s tremor. In addition to this, deep brain stimulation is able to treat muscle tonus, improve motor speed and reduce allodynia.