What is the dosage of bevacizumab?



Bevacizumab dosage according to 21 days once, for different diseases dosage is very different, specific need to combine with the clinical situation to determine.

Bevacizumab is mainly used for the treatment of metastatic colon cancer, advanced, metastatic or recurrent non-small cell lung cancer, recurrent glioblastoma and other diseases. Continued bevacizumab treatment is recommended until disease progression.

For treatment of metastatic colorectal cancer, 5 mg/kg body weight administered every two weeks. or 7.5 mg/kg bw every 3 weeks; for advanced, metastatic or recurrent non-small cell lung cancer, the recommended dose is 15 mg/kg bw every 3 weeks.

For the treatment of recurrent glioblastoma, the recommended dose is 10 mg/kg body weight every two weeks. This should be determined in the context of the clinical situation.

Bevacizumab should be administered for more than 90 minutes for the first time, and the dosage time can be gradually shortened if it is well tolerated, and the dosage can be appropriately reduced or targeted treatment can be carried out in the event of diarrhea, nausea, bleeding, and other adverse reactions, and if necessary, the treatment should also be suspended.

Bevacizumab need to be closely observed during the medication whether the patient has bleeding perforation, but also need to do a good job of lowering blood pressure, found abnormal timely treatment; in addition, pregnant women, women in pregnancy is prohibited, women in childbearing years to do a good job of contraception.

Drugs should be used under the guidance of a professional doctor, not blindly self-medication, in order to avoid adverse effects.