Atrophic gastritis is a chronic gastritis characterized by atrophy of the gastric mucosal epithelium and glands, reduction in number, thinning of the gastric mucosa, thickening of the mucosal base, or with pyloric glandular hyperplasia and intestinal glandular hyperplasia, or with atypical hyperplasia. A small or large amount of upper gastrointestinal bleeding may occur in those with gastric mucosal erosion. The treatment mainly includes the following aspects: 1. To address the cause of the disease: the foci of infection in the nose, mouth and throat should be removed, and smoking and alcohol should be avoided. Diet should be soft, easy to digest, avoid too rough, avoid food containing strong spicy seasonings or taking drugs that stimulate the stomach. Geriatric gastric mucosa of varying degrees of atrophy and intestinalization is difficult to reverse, when there is active inflammation should be actively treated. 2, drug treatment: (1) eradication of H. pylori infection. (2) Gastric mucosal protective agent aluminum thioglycollate tablets or suspension: 1 hour before meals and at bedtime. Colloidal bismuth subcitrate half an hour before meals and at bedtime, should not be used for more than 8 weeks. Teprenone, half an hour before meals and at bedtime, should not be used for more than 8 weeks. (3) H2 receptor blockers: ranitidine, famotidine, cimetidine, can not be taken orally can be used for intravenous drip. (4) Gastric stimulants: domperidone, cisapride, metoclopramide, etc. are taken orally. (5) Digestive aids and dilute hydrochloric acid: for chronic atrophic gastritis, without mucosal erosion, especially gastric body atrophic gastritis can be used as a compensatory treatment, such as multi-enzyme tablets or pancreatic enzyme tablets; pepsin combination; (6) for combined pernicious anemia need lifelong injection of vitamin B12: once daily. For iron deficiency anemia, iron supplementation, ferrous sulfate tablets 0.3g or ferrous succinate 100mg along with vitamin C, orally. Some trace elements such as zinc, selenium, beta carotene, etc. can be supplemented appropriately. 3, diet rules: eat less spicy food, eat less pickled products, smoked food; avoid smoking and alcohol, light diet. The above is the treatment of atrophic gastritis with erosion, but the specific treatment should be under the guidance of clinicians, according to the patient’s condition, standardized treatment.