Which leads of the electrocardiogram are specifically altered in acute anterior wall myocardial infarction

In acute anterior wall myocardial infarction, the ECG changes specifically in leads V3, V4 and V5.
Coronary artery blood supply to the myocardium is distributed regionally, and an occlusion of a coronary artery causes necrosis in a part of the myocardium it supplies, so its ECG changes are segmental. Therefore, ischemic injury is seldom confined to a single lead, but should occur in at least two or more adjacent leads.
The anterior interventricular wall corresponds to leads V1-V3, the forearm corresponds to leads V3-V5, and the extensive anterior wall corresponds to leads V1-V6 and is supplied by the left anterior descending vessel. The anterior-posterior wall corresponded to leads V7-9 and was supplied by the left echogenic branch or right coronary vessels. The infarct site determined by ECG broadly identifies the infarct-related vascular lesion and helps in treatment.
An abnormal ECG examination requires aggressive diagnosis and treatment.