The risk factors for cirrhosis and liver cancer in chronic hepatitis B patients are similar, which means that the more risk factors a patient has, the closer he or she is to cirrhosis and liver cancer. However, it does not mean that if you have one or two “risk factors”, you will definitely develop cirrhosis or liver cancer. The more “risk factors” you have, the more likely you are to get cirrhosis or liver cancer, but the list of these “risk factors” is just to make you more alert. Risk factors include: 1. Older patients, male, >40 years old when HBeAg conversion occurs. 2. Persistent elevation of ALT. 3, viral HBV DNA > 2000 IU/ml (equivalent to > 104 copies/ml), HBeAg continues to be positive. 4, HBeAg-negative hepatitis B. Although HBV DNA is low (<2000 lU/ml), those with B or C genotype infection and high levels of HBsAg (≥1000 IU/ml) are also at risk of liver cancer. This also suggests that patients with chronic hepatitis B should seek to test for the genotype of HBV. 5, HBV genotyping is type C. 6, HBV infection and combined with hepatitis C virus (HCV), hepatitis D virus (HDV) or HIV (HIV) infection. 7.Alcoholism or obesity. 8.Progressing to cirrhosis (including compensated cirrhosis and decompensated cirrhosis). 9, Hepatitis B patients with diabetes or their immediate family members with a history of liver cancer. Exposure to aflatoxin.