Special drugs for rheumatic diseases should be formulated according to the specific type of rheumatic disease of the patient, as follows: 1, for gouty arthritis in rheumatic diseases, the special drug is febuxostat. 2, for patients with rheumatoid arthritis, the special drug is methotrexate, leflunomide, such as immunosuppressants and biologics. 3, for patients with systemic lupus erythematosus, the special drug is glucocorticoid and Immunosuppressants, such as cyclosporine soft capsules and other drugs. Therefore, to talk about specific drugs, first of all, it is necessary to clarify the diagnosis of rheumatic disease, and it is necessary to carry out the examination of antinuclear antibody, anti-DNA spectrum, rheumatoid factor, anti-CCP antibody, blood sedimentation, C-reactive protein and so on. Through the examination to clarify the specific cause of rheumatic disease, and then proceed to the next step of treatment.