At present, there are three main ways to lose weight: First, diet and exercise control, dietary recommendations for low-calorie or very low-calorie diet, the amount of calories per day should be between 1400-1600 kcal or very low calories should be less than 800 kcal. For exercise, aerobic exercise is recommended for at least 1 hour per day. Second, drugs, generally at present the only domestic approved drugs can be used for weight loss mainly orlistat capsules and GLP-1 inhibitors, with liraglutide and exenatide as the main representative. Orlistat capsules are prone to cause steatorrhea, while the application of liraglutide and exenatide requires strict screening of patients for suitability. The application of GLP-1 inhibitors for weight loss is not recommended if the patient has a family history of thyroid cancer as well as significantly elevated calcitonin. Third, cut stomach surgery, but this method is mainly applicable to extremely severe obese patients, and for general obese patients are recommended to diet and exercise control, if the diet and exercise control is not ideal, you can add medication appropriately.