The causes of dry and painful nose are dry rhinitis, atrophic rhinitis, chronic nasal vestibulitis, atropine adverse reaction and so on. 1. dry nasal wash salt, atrophic rhinitis: this is a kind of chronic inflammation of the nasal mucosa, which is usually associated with climate abnormality, environmental pollution, long-term use of medication and other factors, the clinical manifestations of dryness in the nasal cavity, the stinging and itching sensation inside the nose, nosebleeds and so on. 2. Chronic nasal vestibulitis: this disease refers to a diffuse inflammation of the nasal vestibular skin, usually associated with long-term exposure to harmful dust stimulation, increased nasal secretion stimulation of the nasal vestibular skin, nose picking or massage of the nasal vestibular skin, etc., clinical manifestations of the nasal vestibule fever, itching, tenderness and dryness. 3. Atropine adverse reaction: this refers to an adverse reaction caused by overuse of atropine, which is a commonly used M cholinergic receptor blocker in clinic, and overuse will inhibit the secretion function of sweat glands, lacrimal glands and mucous glands and other types of glands in the body, resulting in dryness of the nasal cavity, pain, etc. It is recommended that people should seek medical treatment. It is recommended that people with the disease should seek medical treatment to identify the cause of the disease under the examination of the doctor in order to carry out targeted treatment.