If you feel chest tightness after stenting, you must do ECG in time to see if there is ST-segment elevation, and also review the cardiac enzyme profile to see if there is any myocardial infarction caused by lumen occlusion. Feeling chest tightness after stenting, this may be related to the patient’s vascular lesions are heavier, the endovascular operation is more complex, resulting in postoperative vascular endothelial instability, etc. At this time, it is recommended to give tirofiban pumping to prevent thrombosis. It also includes in-stent restenosis due to the patient’s unregulated medication or clopidogrel resistance. After stenting, chest tightness occurs, at this time must bed rest, avoid strenuous exercise, but also to maintain a good state of mind, do not be nervous and anxious. Some patients have already had acute infarction, and after PCI, the area of myocardial necrosis is large, and there are post-infarction heart failure, vascular entrapment during imaging, pericardial compression caused by the guidewire penetrating the blood vessel, and combined lung disease, etc. At this time, it is necessary to improve the electrocardiogram, cardiac ultrasound and other examinations in time, and according to the situation to decide the next step of treatment. The symptom of chest tightness after stenting should not be taken seriously, and it is necessary to consult a doctor in time to avoid delaying the condition.