The treatment of intermediate type of anemia includes blood transfusion, iron chelator, hematopoietic stem cell transplantation and so on. 1. Blood transfusion: for those with severe anemia, blood transfusion can be given in a standardized manner in the clinic. 2. Iron chelator: Iron chelators such as deferoxamine are usually given after dozens of blood transfusions and when the iron load is too heavy. 3. Hematopoietic stem cell transplantation: it is the most effective method to cure intermediate type of anemia. 4. Splenectomy: Splenectomy can be used when there is obvious hypersplenism, or when there is a high need for blood transfusion, or when there are symptoms of compression by a huge spleen. In addition to the above methods, the disease can also be treated by gene regulation and gene replacement. It is important to note that the adverse effects of intermediate type of anemia can be minimized through “early detection, early diagnosis and early treatment”, and patients are advised to build up confidence in treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.