The clinical size of oxaliplatin is 50mg per pill, and it usually takes 4 pills. The domestic one is 180 yuan per dose, and the imported one is about 2300, which means that the domestic drug needs 720 per cycle and the imported one more than 9000. Oxaliplatin is usually not used alone, but usually in combination with fluorouracil-based drugs for the treatment of gastrointestinal adenocarcinoma, so that each cycle of chemotherapy requires about 3000 to 12,000. The common side effects of oxaliplatin include gastrointestinal reactions and bone marrow suppression, and the other is neurotoxic reactions, mainly manifested as dullness and abnormal sensation, which will be aggravated in case of cold, but most of them are reversible, so it is necessary to pay attention to keeping warm during the use of the drug, wash face, brush teeth and rinse mouth with warm water.