The vast majority of patients with chronic granulocytic leukemia require long-term medication. Chronic granulocytic leukemia is a clonal disease originating from hematopoietic stem cells. Currently, the drugs used to treat chronic granulocytic leukemia are mainly tyrosine kinase inhibitors, such as imatinib, nilotinib and dasatinib. 1. In the chronic phase, it can be treated as a chronic disease and controlled by adherence to medication. With daily oral medication and regular checkups, the disease can be effectively controlled without the need for chemotherapy or transplantation. However, the fear is that if you cannot adhere to the medication, it is easy to enter the accelerated stage or even the acute stage, and the survival time is not optimistic. 2. If patients continue to take oral medication for more than 2 years, and there is no tendency for the disease to recur, the dosage of the drug can be gradually reduced under the guidance of the physician, until the drug is eventually discontinued. However, after stopping the medication, the patient should continue to be observed to prevent the disease from recurring. It is recommended that patients with chronic granulocytic leukemia take the medication under the guidance of a doctor and never stop taking the medication on their own to prevent the disease from progressing.