Dizziness and inability to stand up refers to dizziness with bilateral lower extremity weakness, which is mainly seen in brainstem lesions, including brainstem tumors, brainstem hemorrhage and brainstem infarction. Most patients with brainstem tumors have a subacute onset. Patients may present with dizziness, headache, nausea, vomiting, as well as bilateral lower extremity weakness, dysphagia and choking on water, and cranial MRI can make a clear diagnosis. Brainstem infarction and brainstem hemorrhage is an acute ischemic cerebrovascular disease, and most patients have an acute onset. In the case of brainstem hemorrhage, most patients have an active onset and may suddenly develop dizziness, nausea, vomiting, as well as dysphagia and choking cough, and patients may also develop weakness of both lower extremities. In the case of brainstem infarction, most patients start in a quiet state or during sleep and can present with dizziness, nausea, vomiting, and weakness of both lower extremities, and cranial CT hypodense lesions. In patients with brainstem hemorrhage, most of the cranial CT examinations are high-density lesions.