The drugs for the treatment of high blood uric acid include drugs promoting uric acid excretion such as benzbromarone, drugs inhibiting uric acid production such as allopurinol, and new uric acid-lowering drugs such as labrylase. 1. Promote uric acid excretion drugs: such as benzbromarone and probenecid. Probenecid is only used in primary hyperuricemia with normal renal function, and Benzbromarone is used in renal insufficiency with creatinine clearance >20ml/min. It is contraindicated in patients with acute stage of gout, severe renal impairment or severe kidney stones. May produce gastrointestinal reactions, liver function abnormalities and other adverse reactions. 2. Inhibit uric acid production drugs: such as allopurinol, febuxostat. Febuxostat is suitable for gout-induced hyperuricemia; allopurinol is suitable for hyperuricemia with excessive uric acid production, recurrent gout and gout stones. Adverse reactions such as gastrointestinal reactions and skin rash may occur. Febuxostat is not used for asymptomatic hyperuricemia people, and allopurinol is contraindicated in severe hepatic and renal impairment and obvious platelet hypoplasia. 3. New uric acid-lowering drugs: such as Labrylase. It belongs to uric acid oxidase, which can decompose uric acid into soluble products. Adverse reactions such as fever, nausea, vomiting and rash may occur.’ It is contraindicated in people who are allergic to the product, women during pregnancy and people with G6PD deficiency. It is recommended to consult your doctor for the specific type of medication to be used, and to use it under your doctor’s guidance in combination with your own condition and in accordance with your doctor’s instructions.