Erosive bone destruction is defined as a malignant bone tumor with no definite boundary of destruction, no sclerotic ring envelope, and gradual migration between the tumor and normal bone. Erosive bone destruction is caused by malignant bone tumors and is also seen in bone infections. A rich diet should contain adequate calcium, vitamin D, and other nutrients. Calcium and vitamin D are essential nutrients that are indispensable for increasing and maintaining bone mass. Protein and other nutrients such as: phosphorus, sodium, magnesium and other minerals also play an important role in maintaining bone health. Improving calcium absorption involves choosing calcium-rich foods. For adults, the recommended daily intake of calcium is 800 mg. You can consciously add more milk and other dairy products to your three meals. You can also eat more seafood, shrimp, broccoli, green leafy vegetables, nuts and dried fruits, etc. You can also take nutrients from pork, eggs, beans and fish, etc. Avoid too much meat and salt, as too much protein and salt will accelerate calcium loss. If you do not get enough calcium and vitamin D from your diet, take calcium supplements and vitamin D supplements in moderation, especially for women after menopause. Among calcium supplements, the most used is calcium carbonate, but calcium carbonate is not suitable for patients with stomach acid deficiency. Calcium citrate and other organic acid calcium, although lower in calcium content, is easier to dissolve than calcium carbonate and is suitable for patients with stomach acid deficiency. Calcium phosphate is not easy to dissolve and is not suitable for patients with chronic renal failure. For renal insufficiency or the need to limit the intake of certain nutrients should be more cautious when choosing. 1.Surgical treatment (1) Massive resection: the tumor and its surrounding normal tissues are removed. The residual bone defect can be repaired by autologous bone inactivation and replantation, large bone graft fusion joint, artificial joint replacement, allogeneic hemi-joint transplantation or autologous fibula head instead of lower radius and upper humerus. (2) Amputation of tumor segment and distal reimplantation: The whole segment of the limb where the tumor is located (including skin, muscle and blood vessels) is amputated, but the main nerve is often preserved, and then the distal end is reimplanted onto the proximal limb. Or the lower limb is rotated 180°, the ankle joint is replaced by the knee joint, and then a prosthesis is installed. (3) Amputation or joint dissection. 2.Chemotherapy Applicable to osteosarcoma, Ewing sarcoma, malignant fibrous histiocytoma, etc. It can be administered intravenously or by regional perfusion. 3.Radiation therapy is applicable to tumors that are sensitive to radiation, such as bone marrow-derived tumors, etc. Radiation therapy can also be supplemented for those who cannot be completely removed by surgery or are not suitable for surgery.