Methylcobalamin and Glutamine are taken together for the simultaneous treatment of central nervous system disorders, peripheral nerve disorders and autonomic disorders. Methylcobalamin is an endogenous vitamin B12, which is mainly used in the treatment of nutritional peripheral nerves; Glutamine can regulate autonomic function and improve psychoneurological symptoms. Both of them are taken together to simultaneously treat central nervous system diseases, peripheral nerve diseases and autonomic nerve diseases, such as cerebrovascular disease, demyelinating lesions, peripheral neuropathy, Parkinson’s disease, anxiety states, etc. It is important to note that methylcobalamin is contraindicated in patients with a history of hypersensitivity to methylcobalamin or any of the excipients in the prescription; allergic reactions, such as rash and itching, may occur with administration. Adverse reactions such as dry mouth, upset stomach, nausea, and vomiting are most common with glutamine. Although there is no conflict between the two drugs, but need to regulate the treatment under the guidance of a doctor, do not blindly take on their own to avoid adverse reactions.