One hand peeling the skin of the other normal consideration is ringworm, chronic eczema, exfoliative keratolysis, etc.. 1. Ringworm: dermatophytes infecting the skin of the hands can cause ringworm. You can use antifungal drugs, such as miconazole, terbinafine, etc.; for the local keratinization of obvious lesions, can be used externally with salicylic acid ointment treatment, so that the keratin exfoliation, to promote the penetration of the drug, usually do not have too much contact with water and irritating chemicals, adhere to the treatment. 2. Chronic eczema: eczema is an inflammatory disease caused by internal and external factors, which may be related to heredity, autoimmunity and metabolic disorders. If the symptoms are mild, glucocorticoid ointment such as dexamethasone cream can be used externally, and calcium-modulated phosphatase inhibitors such as tacrolimus ointment and pimecrolimus cream can be used externally; antihistamine drugs such as loratadine can also be taken orally as prescribed by the doctor. 3. Exfoliative Keratolysis: This is a kind of superficial exfoliative skin disease that occurs in the palm and plantar area, and a few of them are unilateral. You can use topical retinoic acid drugs to promote exfoliation, but also can use urea ointment, vitamin E cream, petroleum jelly ointment to moisturize the skin and alleviate the symptoms. It is recommended that patients who have one hand peeling skin and the other hand is normal to go to the hospital in time to find out the cause of the disease and then symptomatic treatment, can not be used privately, to avoid leading to serious adverse reactions.