Generally more than three months of continuous use of hormones is considered long-term medication, so taking hormones for six months belongs to the long-term. Some autoimmune diseases, such as connective tissue disease, systemic lupus erythematosus, dry syndrome, dermatomyositis, vasculitis, etc., is the need for long-term use of hormones. Long-term use of hormones may have various complications, such as osteoporosis, diabetes, hypertension, peptic ulcer, medical Cushing’s syndrome, and concurrent infections. Need should be noted that the allergy to hormones is prohibited, hypertension, peptic ulcer, psychosis, electrolyte metabolism abnormalities, myocardial infarction, glaucoma, tuberculosis, diabetes mellitus, osteoporosis and other patients should be used with caution. Hormones should be used under the guidance of a doctor, and should not be used on their own or increase or decrease the dosage.