How to deal with LDL 4.03mmol/L cannot be generalized. Simple elevated LDL usually requires lifestyle modifications, and if the elevation is combined with cardiovascular disease, medication such as atorvastatin is required as prescribed by the doctor. The normal value of LDL cholesterol is 0-3.37 mmol/L, and 4.03 mmol/L exceeds the normal value. Patients who are not comorbid with other underlying diseases can be controlled by lifestyle modification without oral medication, controlled diet, reduced intake of high-fat foods, increased physical activity, and regular LDL monitoring. Patients with cardiovascular and cerebrovascular diseases should be given lipid-lowering drug therapy, which can be treated with oral statins, commonly used drugs include atorvastatin, etc., and ezetimibe is added if the effect is poor, and subcutaneous injections of PCS K9 inhibitors can be given if necessary, to control LDL level to below 1.8 mmol/L liter, to avoid further aggravation of atherosclerosis. Elevated LDL cholesterol levels should be evaluated for risk and treated under the supervision of a physician.