A sudden lack of interest in anything could be a depressive mood. Depression has relatively strict clinical criteria, such as the presence of depressed mood, delayed reaction to thinking, reduced speech and movement, accompanied by poor sleep, poor diet, low self-evaluation, self-guilt and self-blame, lack of pleasure and interest, accompanied by suicidal and self-injurious thoughts and behaviors. If you belong to the above-mentioned symptoms, it seriously affects your work, study, and social function. Depression is diagnosed only if the above symptoms occur for the vast majority of the day and last for more than two weeks. If the sudden appearance of disinterest in anything can be observed mainly, for which it can be observed for more than two weeks. If the diagnosis of depression is met, systematic and standardized treatment is needed. Antidepressant treatment and psychotherapy can achieve clinical cure, which is a very important clinical treatment option for this condition.