The extra-intestinal manifestations of irritable bowel syndrome mainly include dizziness, headache, panic, frequent urination, anxiety, depression and tension. 1. Dizziness, headache: because irritable bowel syndrome may be due to the patient’s long-term mental tension, resulting in plant nervous system dysfunction, causing intestinal dysfunction and other related. At the same time, mental tension will lead to increased secretion of adrenal hormones in the body, the patient’s heart rate accelerated, brain vasoconstriction, blood pressure increases easily after dizziness, headache symptoms. 2. Panic: Due to the abnormal gastrointestinal tract dynamics caused by irritable bowel syndrome, the nutrients in the food cannot be absorbed properly, if not treated in time, malnutrition or anemia may occur, which cannot provide enough energy, thus leading to panic symptoms. 3. Frequent urination: With the development of irritable bowel syndrome, it may lead to the decline of the patient’s immunity, and the urinary system is susceptible to bacterial infection, such as cystitis may lead to redness, swelling and congestion of the patient’s bladder, which may easily lead to the symptom of frequent urination. 4. Psychosomatic abnormalities: some patients still have different degrees of psychosomatic abnormalities, such as anxiety, depression, nervousness and so on. Patients with the above symptoms should go to the hospital in time for relevant examinations, and under the guidance of professional doctors to clarify the cause of the disease and give targeted treatment.