Cold deficiency of the spleen and stomach, also known as deficiency of cold in the middle jiao and deficiency of spleen and stomach yang, refers to the deficiency of spleen and stomach yang qi, weakening of yang qi warming ability, and the appearance of a series of cold symptoms, which are mainly related to the diet and the innate poor physique. The main manifestations are fear of cold, edema, lack of warmth in the limbs, diarrhea, abdominal pain and so on. Spleen and stomach cold and kidney yang deficiency are closely related, spleen and stomach yang deficiency is often accompanied by kidney yang deficiency symptoms, such as dizziness, waist and knee cold pain, fear of cold limbs cold, the lower limbs are especially obvious, mental depression, loss of libido, men’s spermatorrhea, women’s uterine cold and infertility, or diarrhea for a long time, diarrhea at five o’clock (diarrhea before dawn), pale tongue, white moss, pulse is thin and feeble, the pulse of the ulna, and so on. For lingering abdominal pain (persistent mild abdominal pain), shortness of breath, weakness, and loose stools, Xiao-Jian-Zhong Granules, Li-Zhong Pills, and Pian-Zi Li-Zhong Pills can be used. Xiao Jianzhong Pellet is used for cold pain in stomach and abdomen, pain that gets better after warming or rubbing, noisy stomach (feeling like hunger, emptiness with burning in stomach), vomiting of acidic water, and so on. Lizhong Pill and Radix Rehmanniae Pill are mainly used to treat cold pain in the abdomen and loose stools. If patients are diagnosed with spleen and stomach deficiency cold, they need to take into account their own situation and actively cooperate with doctors to take relevant treatment measures to avoid delaying the condition.