Drainage tube can usually be removed in about one week after total mastectomy. The time of drainage tube removal varies from person to person, depending on the amount of drainage flow and whether the wound is infected, etc., so it can’t be generalized. Patients are advised to take the next step under the guidance of the doctor and not to make any unauthorized decisions. Total mastectomy is a common surgical procedure in clinical practice. Generally, total mastectomy requires extensive flap excision, and to avoid subcutaneous fluid accumulation after surgery two drains will be placed, which are usually placed in the axilla and the anterior chest wall. The main purpose is to empty the fluid under the wound in time. Due to the wide range of breast surgery, especially total mastectomy is easy to cause blood or fluid accumulation under the skin flap, in order to reduce the chance of infection as well as to favor the wound healing, the drainage tube is often placed in the postoperative period, and the drainage flow is less or there is no drainage fluid can be removed. In daily life, patients should maintain a good mood, do not have too much psychological pressure, and eat a light diet. After the operation, the patient should actively cooperate with the doctor for the next step of rehabilitation.