Urine protein plus or minus number indicates that there is protein in the urine, but the amount is not a lot, it is mainly seen in the following diseases: a. Urinary tract infection, urinary tract infection can have positive nitrite, leukocytosis, urine protein plus or minus number, etc. The main symptoms are urinary frequency, urinary urgency, painful urination, this urine protein belongs to the tissue proteinuria, is due to inflammation, treatment is given antibacterial anti-inflammatory. This kind of urine protein is caused by inflammation of the glomerulus, if the amount of urine protein is small, you can temporarily give oral ACEI or ARB and other drugs, you can also use Huang Kui capsule, nephritis four flavors capsule and other Chinese medicine for treatment. Temporarily without hormones and immunosuppressants. The actual nephritis is caused by inappropriate medication, and the urine routine can be seen with urine protein plus or minus numbers. The reason for the production of protein is due to the inflammation of the interstitial kidney, symptoms such as back pain, treatment is generally given hormone therapy.