If metastasis occurs even after total thyroidectomy, it means that the tumor cells have already been transferred into the blood or lymphatic system, and then colonize and grow in the metastatic site, so it is recommended to consult a doctor in time and follow the doctor’s advice to treat the disease actively. At present, the growth characteristics of the tumor cannot be completely determined, and metastasis cannot be completely controlled by clinical treatment, and metastasis may occur even after total resection of the thyroid gland. The main reason is that some of the tumor cells have entered the blood system or lymphatic system before the resection, and then along with the blood or lymphatic circulation, they move in the body, settle in the local area and proliferate, and then form metastatic tumor. After the emergence of the corresponding situation, the whole body should be scanned by PET-CT to determine the specific site of metastasis, and under the guidance of the clinician, iodine 131 treatment, radiotherapy and chemotherapy should be carried out, and the commonly used chemotherapeutic drugs include cisplatin and paclitaxel.