Patients with myocardial ischemia can take nifedipine extended-release tablets or timosartan. Which drug is good can not be compared, according to the indications and contraindications of the drug and the patient’s own situation to choose the appropriate drug treatment. 1. Nifedipine extended-release tablets: belonging to the calcium ion antagonist, the drug can dilate the coronary artery, improve coronary blood supply, thus improving the symptoms of myocardial ischemia. Allergy, cardiogenic shock, pregnant and lactating women are prohibited. Adverse reactions include edema, gastrointestinal discomfort, dizziness, nausea and vomiting. 2. Timosartan: belonging to angiotensin receptor antagonist, it can inhibit vascular smooth muscle contraction, promote vascular smooth muscle diastole, reduce vascular resistance, and at the same time can improve ventricular remodeling, also applicable to patients with myocardial ischemia. It is contraindicated in patients with allergy, pregnancy, lactation, biliary tract disease, severe hepatic insufficiency and severe renal insufficiency. Adverse reactions such as dizziness, cough, chest tightness, panic, nausea and vomiting may occur after taking the drug. Therefore, patients with myocardial ischemia should go to the hospital in time and choose the appropriate medication under the guidance of the doctor.