Milled glass nodules are generally defined as changes in the form of milled glass nodules suggested by a CT scan of the lung. If a grinding glass nodule is diagnosed as lung cancer, treatment with targeted agents may be considered, but targeted agents cannot be the treatment of choice for grinding glass nodules. When the ground-glass nodule is not lung cancer, it also cannot be treated with a targeted agent. For ground-glass nodule-like lung cancer, once detected, the first treatment option that should be considered is radical surgery rather than targeted drug therapy. Targeted therapy is a kind of adjuvant therapy for patients with middle and late stage lung cancer and those who cannot undergo surgery, and it is often combined with surgery, radiotherapy, chemotherapy, immunotherapy and traditional Chinese medicine in the process of lung cancer treatment. If the patient is older, has more underlying diseases, has poor physical condition, cannot tolerate surgery, and the ground-glass nodule needs clinical intervention, CT-guided puncture of the ground-glass nodule can be performed and sent for pathological diagnosis and immunohistochemistry. When the pathological diagnosis of adenocarcinoma is confirmed, genetic testing is needed, and when the driver genes correspond to the targets, targeted therapy can be performed. Ground glass nodules are not necessarily lung cancer, but may also be caused by general benign nodules or infections, etc. For benign nodules, no special treatment is needed, and regular observation is sufficient. For benign nodules, regular observation is enough. For infections, sensitive antibiotics are needed to treat the infection. When grinding glass nodules are found in the lungs, the nature of the lesion should be clarified under the guidance of the doctor and standardized treatment should be carried out.