High tumor-associated antigen 125 can be seen in oncological diseases such as gastrointestinal tumors, but also in benign diseases such as pelvic inflammatory disease, which should be treated by doctor in time, after complete examination, including medication, surgery and other treatments. 1. Tumor-associated antigen 125 is a kind of glycoprotein tumor-associated antigen, whose elevated value can be seen in gastrointestinal and female reproductive tract tumors, such as ovarian cancer, gastric cancer, intestinal cancer, etc. According to the different accompanying symptoms, it is necessary to complete different examinations. If accompanied by vomiting blood, black stools, gastroenteroscopy, abdominal CT and other examinations are needed. If accompanied by vaginal bleeding, gynecological ultrasound is needed to be perfected, etc. After clarifying the source of cancer, active treatment is needed, which is mostly surgery to remove the primary lesion. Oral antitumor drugs such as carmustine and capecitabine can also be used, and radiotherapy such as cisplatin can also be used. 2. High tumor-associated antigen 125 can also be seen in benign reactions, such as pelvic inflammatory disease, pancreatitis, etc. If pelvic inflammatory disease, you need to improve the hysteroscopy examination, blood routine, leukorrhea secretion examination, etc. The treatment is mainly medication, such as clindamycin, metronidazole, cefixime, etc. In daily life, you should pay attention to the vaginal hygiene and cleanliness. In daily life, you should pay attention to vaginal hygiene and cleanliness, and change your underwear frequently. If the pancreatitis needs to improve the pancreatic enzyme series, abdominal ultrasound, abdominal CT, etc. Mild pancreatitis can be treated with drugs such as growth inhibitors, octreotide, omeprazole, etc.. Severe pancreatitis may require surgical incision and drainage. Tumor-associated antigen 125 is high once found to be elevated, should promptly consult a doctor, under the guidance of the doctor standardized examination and treatment.