Generally, people who have undergone biopsy will have a little pain at the biopsy site when the gauze is removed the next day, but the specific situation varies from person to person. Pathologic examination has become a commonly used clinical examination method, which can clarify the benign or malignant nature of lesions and is the gold standard for diagnosing diseases. Whether or not there will be pain when removing the gauze the day after the biopsy is related to many factors, such as the size of the biopsied tissue, the size of the wound, and the patient’s pain threshold, etc. Generally, the gauze will be removed the next day after the biopsy. There is usually some pain when the gauze is removed the next day, and the degree varies from person to person. For small biopsies, small wounds, and patients with high pain thresholds, there will be only a little pain when the gauze is removed the next day, whereas for large biopsies, large wounds, and patients with low pain thresholds, there will be a greater amount of pain. In addition to this, the area after the biopsy needs to be sterilized regularly and treated with dressing changes to prevent and treat infections to facilitate wound healing.