Elevated ferritin can be seen in the following tumors: acute leukemia, Hodgkin’s disease, lung cancer, colon cancer, liver cancer, and prostate cancer. Detection of ferritin has diagnostic value in metastatic tumors of the liver. 76% of patients with liver metastases have ferritin levels higher than 400 μg/L. When liver cancer is present, low AFP measurements can be supplemented with ferritin measurements to improve diagnosis. Ferritin is also elevated in cases of hyperpigmentation, inflammation, and hepatitis. The elevation may be due to cell necrosis, blocked erythropoiesis or increased synthesis in tumor tissue.