There are many diseases that cause endometrial thickening, the common clinical ones are as follows: 1. Hormonal disorders. The growth of the endometrium is affected by the hormone level in the body. If the hormone level in the body is out of balance and cannot control the growth of the endometrium, endometrial thickening will occur, which may also be accompanied by irregular vaginal bleeding. 2. Inflammatory disease. Viral or bacterial infection can lead to endometritis and endometrial thickening. 3, malignant tumor. The common ones are endometrial cancer, which mostly occurs in perimenopausal women. The clinical manifestation is vaginal bleeding that does not stop, or vaginal bleeding that occurs again after menopause. The imaging examination shows significant thickening of the endometrium. Regardless of the cause of endometrial thickening, it needs to be treated promptly. Pay attention to a light diet, take rest, keep your mood relaxed and try not to take birth control pills.