Nitroglycerin ointment how long to cure anal fissure does not have a unified theory of disease, must be based on the patient’s application of the drug to judge, usually in 1-2 months can be a better cure for anal fissure. Nitroglycerin ointment is mainly used for the treatment of anal fissure and relief of pain caused by anal fissure, local application of the drug can relax the anal sphincter, relieve spasm, alleviate the symptoms, as well as relaxation of intravascular smooth muscle, vasodilatation, increase the local blood scale of blood vessels, and promote the healing of ulcers. This medication has been shown in clinical studies to be effective in relieving anal fissures and fissure-related pain. The study was also conducted over a 2-month period, and the group that used nitroglycerin ointment after 2 months showed a significant decrease in anal fissure pain scores and a significantly higher degree of anal fissure relief than the control group. In the case of old anal fissures, many fissures have formed chronic ulcers, surrounded by fibrosis, the use of nitroglycerin can not make the fissure healing, but only to control the symptoms, most of these fissures need to be treated surgically in order to be cured.