When acute abdominal pain occurs, it is recommended to go to the hospital immediately to diagnose the cause of the disease, and on the basis of a clear diagnosis, drugs such as scopolamine and ibuprofen can be used for pain relief. In addition, the cause of the disease should be treated, such as the use of norfloxacin and other drugs, surgical treatment. The cause of acute abdominal pain is more complex, abdominal trauma, gastrointestinal infectious diseases such as gastroenteritis, appendicitis, etc., autoimmune diseases such as purpura, etc., gastrointestinal tract functional diseases such as irritable bowel syndrome, etc. may cause abdominal pain. Hasty use of medication may mask the condition, which is not conducive to the assessment of the condition. It is recommended to go to the hospital in a timely manner to make a definitive diagnosis before intervening with medication. On the basis of standardized etiological treatment, pain can be improved by using drugs such as scopolamine to relieve gastrointestinal spasm, or analgesic drugs such as ibuprofen and octreotide to improve pain symptoms. For functional or neurological pain such as irritable bowel syndrome, symptoms can be improved by using antidepressant or anxiety drugs such as amitriptyline and promethazine. In addition to the cause of treatment, such as bacterial gastroenteritis should use antibiotics such as norfloxacin, appendicitis should be timely surgical treatment. It is recommended to go to the hospital in time for acute abdominal pain; the above drugs should be used under the guidance of the clinician.