If the crying is not relieved after timely soothing, pathological factors such as gastrointestinal discomfort, calcium and vitamin D deficiency can be considered, and it is recommended to go to the hospital for examination and treatment after clarifying the causes. I. Physiological factors: baby hunger, holding urine, the environment is too cold or too hot, frightened, etc., can cause the child to cry at bedtime, if the mental state is good, not accompanied by other discomfort, such as fever, loss of appetite, etc., are normal, parents are advised to promptly soothe, can make the baby restore calm; 2. pathological factors: 1. gastrointestinal discomfort: in addition to the baby always cry at bedtime, also accompanied by a decrease in the number of stools, dry stools, loss of appetite, etc, Dry stools, loss of appetite and other symptoms, mostly considered to be caused by infant gastrointestinal discomfort. If the symptoms are mild, it is recommended to reduce the amount of breastfeeding, massage the baby’s abdomen or apply hot compresses, if there is no relief after daily care, go to the hospital for treatment; 2, lack of calcium and vitamin D: calcium and vitamin D deficiency can lead to increased neuromuscular excitability and easy crying during sleep. It is recommended to go to the hospital to check the trace elements, if diagnosed, can be under the guidance of the doctor appropriate supplementation, parents usually need to take the baby appropriate sun exposure, diet can also be appropriate to eat food containing calcium and vitamin D, such as egg yolk; 3, other: baby suffering from intestinal entrapment, intestinal obstruction, acute cholecystitis, chronic appendicitis and other diseases can also appear crying in bed, should promptly consult a doctor to clarify the cause, according to the cause of Treatment. Note crying is the baby’s way of expressing emotions and needs, parents usually need to closely observe, if a long time crying, need to pay attention to, if necessary, need to seek medical attention.