Bone marrow aspiration (bone aspiration) is a common clinical test, and many patients are very frightened when they hear that they have to undergo bone marrow aspiration. I have done bone aspiration for thousands of patients, and now I would like to tell you about the process of bone aspiration. To use a more graphic analogy, it is like drilling for oil at the bottom of the sea. For sternal bone puncture and anterior superior iliac spine bone puncture, the patient is lying down, and for posterior superior iliac spine bone puncture, the patient is lying on his side and flexing his lower limbs. The needle is then inserted into the bone, passing through the skin (water surface) and subcutaneous tissues (seawater layer) to reach the bone surface in turn and then starts to rotate the needle (that is, drill into it), passing through the bone cortex (submarine rock layer) and then entering the bone marrow cavity (submarine oil field), and then using an empty syringe to extract a little bone marrow fluid, which only requires 0.5 ml for smear examination and 5-10 ml for flow, genetic and chromosomal examinations. Generally speaking, the puncture part is not particularly painful, and there is a little soreness and swelling when the bone marrow fluid is drawn. This operation is very simple, usually completed within 10 minutes, and is an outpatient operation, and the patient can leave when it is over.