There are two types of anal itching: idiopathic and secondary. Idiopathic anal itching is generally uncaused and has a genetic predisposition. The prevention and treatment should be to keep the area clean and dry, without hot water, without alkaline soap, and without scratching with the hands. When itchy, you can apply topical anti-itch cream or hormonal ointment (such as fluorescein acetate ointment, etc.); if the itchiness affects your sleep at night, you can take a Sai Gentis tablet orally before going to bed. The perianal area is a place where various microorganisms (bacteria, fungi and parasites) live and multiply. Pinworms are a common cause of anal itching in children. It can be cured with deworming treatment and frequent changing and washing of lining pants. The perianal skin is moist and is one of the most common sites for fungal infections. It is more common to see Candida albicans infection, miconazole, clotrimazole cream and other topical applications can be effective. The actual anal itch is also present in viral infections such as anal condyloma and infectious molluscum contagiosum; anorectal diseases cause anal itch. These patients must clean the perianal area every night and treat the anorectal disease in a timely manner. Some skin diseases can also cause anal itching, such as lichen planus, sclerosing atrophic moss, Bowen’s disease, and anal eczema. For this type of skin disease, corticosteroid-containing ointment can be applied locally, which has anti-inflammatory and anti-itching effects. Anal itching caused by systemic diseases is also not uncommon, such as lymphoma, diabetes, vitamin A and D deficiency, etc. Regardless of the cause of anal itching, should pay attention to several points: (1) keep the anus clean, as far as possible every night to clean the anus; (2) cleaning the anus should use warm water, generally do not have to use soap, especially not alkaline heavy soap; (3) underwear should be diligent change, do not wear artificial fiber underwear; (4) keep the anus dry; (5) anal itching can not be scratched with your hands, can be coated with anti-itch cream or hormone cream.